Rinossinusite Fúngica Invasiva por Fusarium solani com Necrose Nasal em Paciente Transplantado Hepático

Henrique Viana Carvalho Botelho; Priscilla da Cunha Leal; Júlia Alves de Senne; Juliana Weiler Medeiros; Leandro Mignot Sobrinho; Amanda Borges Nunes Ximenes

doi:10.36489/nursing.2026v31i332p12828-12851

Authors

Henrique Viana Carvalho Botelho Otorrinolaringologia - Instituto de Otorrinolaringologia da Gamboa https://orcid.org/0009-0006-4912-1665
Priscilla da Cunha Leal Residente de Otorrinolaringologia do Instituto D’or - Rio de Janeiro
Júlia Alves de Senne Medicina - Otorrinolaringologia. IOG - Instituto de Otorrinolaringologia da Gamboa https://orcid.org/0000-0002-3665-1134
Juliana Weiler Medeiros Otorrinolaringologia. Idor - Instituto D’or de Ensino e Pesquisa https://orcid.org/0009-0009-5161-8066
Leandro Mignot Sobrinho Otorrinolaringologia. IOG - Instituto de Otorrinolaringologia da Gamboa https://orcid.org/0000-0003-3552-2688
Amanda Borges Nunes Ximenes Instituto de Otorrinolaringologia da Gamboa https://orcid.org/0000-0002-8873-6076

DOI:

https://doi.org/10.36489/nursing.2026v31i332p12828-12851

Keywords:

Fungal rhinosinusitis, Fusarium solani, Liver transplantation, Nasal necrosis, Immunosuppression

Abstract

Introduction: Invasive fungal rhinosinusitis (IFR) is a serious and uncommon infectious condition, especially in immunocompromised patients, such as liver transplant recipients. The genus Fusarium, although less frequent than Aspergillus and Mucorales, can cause fulminant infections
with mucocutaneous involvement and risk of systemic dissemination. This study reports the case of a 66-year-old male patient who underwent liver transplantation and developed nasal necrosis after fungal rhinosinusitis caused by Fusarium solani. Objective: The objective is to discuss the
clinical, diagnostic, and therapeutic aspects of ISR caused by this pathogen in the context of immunosuppression. Method: The methodology used comprised a case study based on clinical records, imaging tests, endoscopy, and histopathological analysis with fungal culture and
identification. Results: Rapid progression of the condition was observed, with extensive tissue involvement, requiring extensive surgical intervention. Conclusion: Analysis of the case reinforces the importance of early diagnosis, targeted antifungal treatment, and multidisciplinary intervention. The rarity and severity of Fusarium infection in the paranasal sinuses justify further scientific investigation of the topic.

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