Relationship of Cytomegalovirus Infection and Autism Spectrum Disorder: A Scoping Review

Authors

  • Douglas dos Santos Oliveira Acadêmico de Enfermagem. Centro Universitário. Rio Branco. Acre. Brasil. https://orcid.org/0009-0003-8159-3126
  • Ruth Silva Lima da Costa Acadêmico de Enfermagem. Centro Universitário. Rio Branco. Acre. Brasil ORCID: https://orcid.org/0009-0003-8159-3126 Ruth Silva Lima da Costa Doutoranda em Epidemiologia em Saúde Pública ENSP/FIOCRUZ. Rio de Janeiro. RJ. Brasil. https://orcid.org/0000-0003-1890-086X

DOI:

https://doi.org/10.36489/nursing.2025v29i320p10509-10518

Keywords:

Autism, Neuropsychiatric development, Congenital infection

Abstract

Autism Spectrum Disorder affects communication, social interaction and behavior, varying in severity, and Cytomegalovirus, a common congenital infection, is linked to neurodevelopmental disabilities. This study aimed to investigate the possible relationship between cytomegalovirus infection and autism spectrum disorder. This is a systematic review that analyzed articles published between 2014 and 2024 in the following databases: Google Scholar, Scientific Electronic Library Online, Latin American and Caribbean Literature in Health Sciences and National Library of Medicine. The possible association may depend on the follow-up time of the population samples analyzed. Although the direct relationship between them has not yet been fully scientifically elucidated, there is a consensus that the infection can compromise neurodevelopment. The divergences in the results found may be associated with methodological differences between the studies, including variations in diagnostic criteria, infection detection methods and control of variables such as genetic predisposition and environmental factors.

Author Biography

Ruth Silva Lima da Costa, Acadêmico de Enfermagem. Centro Universitário. Rio Branco. Acre. Brasil ORCID: https://orcid.org/0009-0003-8159-3126 Ruth Silva Lima da Costa Doutoranda em Epidemiologia em Saúde Pública ENSP/FIOCRUZ. Rio de Janeiro. RJ. Brasil.

Doutoranda em Epidemiologia em Saúde Pública (FIOCRUZ/ENSP). Graduada em Enfermagem pela Universidade Federal do Acre (UFAC); Especialista em Gestão de Sistemas e Serviços de Saúde (UFAC) e em Educação Profissional na Área da Saúde: Enfermagem (FIOCRUZ/ENSP). Mestre em Ciências da Saúde (UFAC). Atua como enfermeira na Secretaria de Estado de Saúde do Acre e no Centro Universitário Uninorte desempenhando as funções de docente, coordenadora adjunta do curso de Medicina, membra do núcleo docente estruturante ( NDE) dos cursos de Enfermagem e Medicina. Tem experiência na área de gestão e planejamento em saúde, atenção à saúde da criança e adolescente e atenção primária em saúde. É revisora de periódicos científicos e membra de comitê de ética em pesquisa. Atualmente tem se dedicado a pesquisa através da coordenação de projetos de iniciação científica com potencial interesse em produtos derivados de plantas amazônicas e também voltada para saúde coletiva com ênfase nas condições crônicas, além da atenção integral à saúde da criança e adolescente e sistematização da assistência de enfermagem

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Published

2025-03-06

How to Cite

dos Santos Oliveira, D., & Silva Lima da Costa, R. (2025). Relationship of Cytomegalovirus Infection and Autism Spectrum Disorder: A Scoping Review. Nursing Edição Brasileira, 29(320), 10509–10518. https://doi.org/10.36489/nursing.2025v29i320p10509-10518

Issue

Section

Systematic Review

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