Biomarcadores na Avaliação da Função Renal e Implicações para o Cuidado de Enfermagem: Revisão Integrativa

Mateus Sampaio de oliveira; Milleny Sampaio da Silva; Raimundo Domiciano de Souza Neto; Izabel Cristina Santiago Lemos de Beltrão

doi:10.36489/nursing.2026v32i339p14713-14760

Autores

Mateus Sampaio de oliveira Universidade Regional do Cariri (URCA) https://orcid.org/0009-0006-4464-4301
Milleny Sampaio da Silva Universidade Regional do Cariri (URCA) https://orcid.org/0009-0006-5566-8296
Raimundo Domiciano de Souza Neto Universidade Regional do Cariri (URCA) https://orcid.org/0000-0003-4148-6601
Izabel Cristina Santiago Lemos de Beltrão Universidade Regional do Cariri

DOI:

https://doi.org/10.36489/nursing.2026v32i339p14713-14760

Palavras-chave:

Biomarcadores, testes de função renal, enfermagem

Resumo

Objetivo: descrever, comparar e sintetizar evidências acerca dos biomarcadores tradicionais e emergentes empregados na avaliação da função renal. Método: revisão integrativa, com busca nas bases CINAHL, LILACS, MEDLINE/PubMed e SciELO, de janeiro a abril de 2026. Resultados: foram incluídos 37 estudos, com predomínio de delineamentos observacionais e ensaios clínicos. Os biomarcadores tradicionais, como creatinina, TFGe e albuminúria, permanecem amplamente utilizados, mas apresentam limitações na detecção precoce. Já biomarcadores como cistatina C, NGAL, KIM-1, IL-18, MCP-1, UMOD e TNFR1/TNFR2 mostraram melhor sensibilidade, valor prognóstico e capacidade de identificar alterações renais em fases iniciais, especialmente quando usados em conjunto. Conclusão: os biomarcadores emergentes ampliam a avaliação da função renal e devem ser empregados como complemento aos marcadores tradicionais, com potencial para qualificar o monitoramento clínico e o cuidado de enfermagem.

Biografia do Autor

Mateus Sampaio de oliveira, Universidade Regional do Cariri (URCA)

Graduando em Enfermagem pela Universidade Regional do Cariri - URCA. Bolsista PET-Enfermagem. Membro do Grupo de Pesquisa em Enfermagem e Saúde do Adulto em Ambiente Hospitalar (GPESAH/URCA).

Milleny Sampaio da Silva, Universidade Regional do Cariri (URCA)

Graduanda em Enfermagem da Universidade Regional do Cariri. Bolsista PET-Saúde. Membro do Grupo de Pesquisa em Enfermagem e Saúde do Adulto em Ambiente Hospitalar (GPESAH/URCA).

Raimundo Domiciano de Souza Neto, Universidade Regional do Cariri (URCA)

Bacharel em Enfermagem pela Universidade Regional do Cariri (URCA). Mestrando pelo Programa de Pós-Graduação em Enfermagem da URCA (PMAE/URCA). Enfermeiro assistencialista do Hospital e Maternidade São Vicente de Paula (HMSVP).

Izabel Cristina Santiago Lemos de Beltrão, Universidade Regional do Cariri

Bacharel em Enfermagem pela Universidade Regional do Cariri (URCA, 2012); Mestre em Bioprospecção Molecular (PPBM/URCA, 2015); Doutora em Etnobiologia e Conservação da Natureza (UFRPE, 2021). Docente do Curso de Graduação em Enfermagem da Universidade Regional do Cariri (URCA). Professora Permanente do Programa de Pós-Graduação em Enfermagem (PMAE/URCA).
Líder do Grupo de Pesquisa em Enfermagem e Saúde do Adulto em Ambiente Hospitalar (GPESAH).
Coordenadora da Liga Acadêmica de Cuidados de Enfermagem em Saúde do Adulto em Ambiente Hospitalar (LACESAH).

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